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Shirit Einav

Academic Appointments

  • Assistant Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology

Key Documents

Contact Information

  • Clinical Offices
    Infectious Disease 300 Pasteur Dr Ln Building Rm L127 MC 5107 Stanford, CA 94305
    Tel Work (650) 724-5243 Fax (650) 723-3474
  • Academic Offices
    Personal Information
    Email Tel (650) 723-8656
    Not for medical emergencies or patient use

Professional Overview

Clinical Focus

  • Infectious Disease

Academic Appointments

Administrative Appointments

  • Assistant Professor (UTL), Department of Medicine, Department of Microbiology and Immunology (2011 - present)
  • Instructor of Medicine, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine (2009 - 2011)
  • Infectious Diseases Fellowship, Division of Infectious Diseases and Geographic Medicine, Stanford University School of Medicine (2004 - 2008)
  • Postdoctoral Fellowship. Supervisor: Dr. Jeffrey S. Glenn, Division of Gastroenterology and Hepatology, Stanford University School of Medicine (2003 - 2004)
  • Medical Internship and Residency, Internal Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA (1999 - 2002)
  • Research Studentship, Supervisor: Dr. Michael C. Carroll., Brigham and WomenÂ’s Hospital and the Center for Blood Research, Harvard Medical School, Boston, MA (1999 - 1999)
View All 7administrative appointments of Shirit Einav

Honors and Awards

  • Research Scholar Grant, American Cancer Society (2014)
  • Clinical Scientist Development Award, Doris Duke Charitable Foundation (2013)
  • Stanford Bio-X Interdisciplinary Initiative Program Award, Stanford, Bio-X (2012)
  • IDSA 2012 IDWeek Investigator Award, Infectious Diseases Society of America (IDSA) (2012)
  • IDSA 2009 Program Committee Choice Award, Infectious Diseases Society of America (IDSA) (July 2009)
  • DDC Pilot/Feasibility Award, Stanford Digestive Disease Center (DDC) (March 2009)
View All 16honors and awards of Shirit Einav

Professional Education

Residency: Beth Israel Deaconess Med Center/Harvard MA (2002)
Fellowship: Stanford University - Infectious Diseases CA (2009)
Board Certification: Infectious Disease, American Board of Internal Medicine (2006)
Internship: Beth Israel Deaconess Med Center/Harvard MA (2000)
Medical Education: Sackler School of Medicine, Israel (1999)
BA: Sackler School of Medicine, Israel, Medical sciences (1994)
View All 7

Courses

2013-14

Graduate and Fellowship Program Affiliations

Scientific Focus

Current Research and Scholarly Interests

The goals of my lab are to better understand virus-host protein interactions, identify host partners conservatively required by multiple viruses, and develop broad-spectrum host-centered antiviral approaches with a high genetic barrier for resistance. We combine novel proteomic approaches, including microfluidics platforms, with molecular virology, biochemical, and genomic approaches to achieve these goals. We focus on viruses from the Flaviviridae family (hepatitis C and dengue), as well as HIV.

Ongoing projects:
1. Mechanisms by which Flaviviridae and HIV hijack intracellular membrane trafficking pathways for mediating viral assembly, release, and direct cell-to-cell spread. We have identified several sorting signals within Flaviviridae proteins that are involved in mediating key steps in the viral cycle. We are currently mapping the interaction networks of these signals with human proteins, and investigating the functional relevance, regulatory mechanisms, and inhibition of these interactions. Additional projects involve interactions with cytoskeleton dynamics proteins, ESCRT machinery and more.
2. Mechanisms of HCV-related cancer. Chronic HCV infection is a major cause of hepatocellular carcinoma and is also associated with non-Hodgkin lymphoma. We study virus-host interactions involved in facilitating viral persistence (a precursor to HCV-related oncogenesis).
3. Molecular mechanisms underlying HCV-HIV co-infection.
4. Furthering novel high-throughput proteomic technologies for screening and mapping virus-host interactomes and for screening small molecule libraries for inhibitors of protein-protein interactions.

Publications

Publication tag cloud

Publication Topics

View All 13

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