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Michelle Monje

Academic Appointments

  • Assistant Professor of Neurology and, by courtesy, of Neurosurgery and of Pediatrics

Key Documents

Contact Information

  • Clinical Offices
    Pediatric Neurology Division 300 Pasteur Dr A343 MC 5235 Stanford, CA 94305
    Tel Work (650) 723-6841 Fax (650) 725-7459
  • Academic Offices
    Personal Information
    Email Tel (650) 736-0885
    Alternate Contact
    Julie Ng Tel Work 650 736 0885
    Not for medical emergencies or patient use

Professional Overview

Clinical Focus

  • Neurology
  • Neuro Oncology

Academic Appointments

Honors and Awards

  • New Faculty Physician Scientist Translational Research Award, California Institute of Regenerative Medicine (CIRM) (2013 - 2018)
  • Basic Science IV Award, California Institute of Regenerative Medicine (CIRM) (2012 - 2015)
  • ‘A’ Award, Alex’s Lemonade Stand Foundation (2012-2015)
  • Peter A. Steck Memorial Award, Pediatric Brain Tumor Foundation (2011)
  • K08 Mentored Clinical Scientist Career Development Award, National Institutes of Neurological Disorders and Stroke (2010 - 2015)
  • Young Investigator Award, Hagerty Foundation for Glioma Research (2006)

Boards, Advisory Committees, Professional Organizations

  • Chair, Brainstem Glioma Working Group, Pediatric Brain Tumor Consortium (2013 - present)
  • Member, Pediatric Brain Tumor Consortium Translational Biology Committee (2012 - present)
  • Institutional Co-PI, Pediatric Brain Tumor Consortium (PBTC) (2012 - present)
  • Member, Children’s Oncology Group (COG) (2011 - present)

Professional Education

Fellowship: Stanford University - Dept of Neurology CA (06/30/2010)
Residency: Brigham and Women's Hospital Harvard Medical School MA (06/30/2008)
Internship: Stanford University CA (06/30/2005)
Medical Education: Stanford University CA (06/13/2004)
Residency: Massachusetts General Hospital MA (06/30/2008)
Board Certification: Neurology, American Board of Psychiatry and Neurology (2008)
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Courses

2013-14

Postdoctoral Advisees

Michael BetleyViola CarettiErin Valdez

Scientific Focus

Current Research and Scholarly Interests

Much of brain development occurs after birth. Maturation of complex neural circuitry necessary for high-level cognitive and motor functions occurs throughout childhood and young adulthood. Central to the process of developing or strengthening a functional neural circuit is the generation of new glial cells for neuronal support, synapse formation and myelination. In some brain regions, such as the hippocampus, new neuron production occurs throughout postnatal life and is believed to subserve normal memory function.

The Monje Lab studies the molecular and cellular mechanisms of postnatal neurodevelopment. This includes microenvironmental influences on neural precursor cell fate choice in normal neurodevelopment and in disease states. Areas of emphasis include neuronal instruction of gliogenesis, cellular contributions to the neurogenic and gliogenic signaling microenvironment, molecular determinants of neural precursor cell fate, and the role of neural precursor cells in oncogenesis and repair mechanisms. As a practicing neurologist and Neuro-oncologist, Dr Monje is particularly interested in the roles for neural precursor cell function and dysfunction in the origins of pediatric brain tumors and the consequences of cancer treatment. As a paradigm of pediatric gliogenesis, we have been focusing on brainstem tumors, whose spatial and temporal specificity bespeak an underlying developmental cause.

Publications

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Publication Topics

View All 13

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