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Manuel Amieva

Academic Appointments

  • Associate Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology

Key Documents

Contact Information

  • Clinical Offices
    Pediatric Infectious Disease 730 Welch Rd 2nd Fl MC 5884 Palo Alto, CA 94304
    Tel Work (650) 721-5805 Fax (650) 725-8040
  • Academic Offices
    Personal Information
    Email
    Not for medical emergencies or patient use

Professional Overview

Clinical Focus

  • Infectious Diseases, Pediatric
  • Pediatric Infectious Disease

Academic Appointments

Professional Education

Fellowship: Stanford University School of Medicine CA (2004)
Residency: Stanford University School of Medicine CA (1999)
Internship: Stanford University School of Medicine CA (1998)
Board Certification: Pediatric Infectious Disease, American Board of Pediatrics (2005)
Medical Education: Stanford University School of Medicine CA (1997)

Courses

2013-14

Postdoctoral Advisees

Ryan HonakerMichael Sigal

Graduate and Fellowship Program Affiliations

Scientific Focus

Current Research and Scholarly Interests

My laboratory studies the strategies pathogens utilize to colonize and subvert the epithelial barrier. We have focused on the epithelial junctions as a target for bacterial pathogens, since the cell-cell junctions serve as both a barrier to infection and also a major control site for epithelial function. In particular, we are interested in how the gastric pathogen Helicobater pylori may cause cancer by interfering with cell signaling at the epithelial junctions. We are also studying how various bacteria cross and invade the epithelium. For example, we recently found that Listeria monocytogenes targets a specialized subset of cell-cell junctions at the tip of the intestinal villi to find its receptor for invasion. We are interested in determining whether this mode of gastrointestinal invasion of the epithelium is also used by other gastrointestinal pathogens.

Publications

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Publication Topics

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