Clinical Focus

• Hematopathology
• Pathology and Laboratory Medicine
• Anatomic/Clinical Pathology

Administrative Appointments

• Co-Director, Immunodiagnosis Laboratory, Stanford (2005 - present)
• Associate Chair for Hematopathology, Stanford (2009 - present)
• Associate Chair for Faculty Development and Diversity, Stanford (2009 - present)

Professional Education

Graduate & Fellowship Program Affiliations

• Pathology

Community and International Work

• Improving Pathology Facilities in Underserved Communities, Sri Lanka 

Current Research Interests

My laboratory studies the tissue expression pattern of proteins that are of potential interest for the diagnosis, prognostic stratification and therapy of patients with lymphoma and leukemia. We are currently investigating prognostic markers in diffuse large B-cell lymphoma such that risk groups can be better defined. We are also interested in the immunodiagnostic and molecular characterization of rare and aggressive hematopoietic tumors such as Natural Killer/T-cell lymphomas, histiocytic malignancies and childhood lymphomas.

Clinical Trials

• Genome, Proteome and Tissue Microarray in Childhood Acute Leukemia Recruiting
• Phase II study of Atorvastatin safety and antitumor effects in non-Hodgkin's Lymphoma Recruiting
• Phase I Intratumoral Dendritic Cell Immunotherapy in Thermally Ablated Liver Metastases Terminated
• Phase I/II Intratumoral DC Immunotherapy With Gemcitabine & XRT in Unresectable Pancreatic Cancer Completed
• Phase II Fludarabine, Cytoxan and FCCAM in Untreated B-Cell Chronic Lymphocytic Leukemia Completed

Publications

• Aggressive EBV-associated Lymphoproliferative Disorder: A Prodrome to Diffuse Large B-cell Lymphoma? Batra R, Medeiros BC, Zehnder JL, Warnke RA, Natkunam Y. Appl Immunohistochem Mol Morphol. 2012; 20 (3): 325-30
• Identification of LMO2 transcriptome and interactome in diffuse large B-cell lymphoma. Cubedo E, Gentles AJ, Huang C, Natkunam Y, Bhatt S, Lu X, Jiang X, Romero-Camarero I, Freud A, Zhao S, Bacchi CE, Martínez-Climent JA, Sánchez-García I, Melnick A, Lossos IS. Blood. 2012
• IgG4-Related Systemic Sclerosing Disease of the Ocular Adnexa: A Potential Mimic of Ocular Lymphoma. Karamchandani JR, Younes SF, Warnke RA, Natkunam Y. Am J Clin Pathol. 2012; 137 (5): 699-711
• LIM domain only 2 protein expression, LMO2 germline genetic variation, and overall survival in diffuse large B-cell lymphoma in the pre-rituximab era. Cerhan JR, Natkunam Y, Morton LM, Maurer MJ, Asmann Y, Habermann TM, Vasef MA, Cozen W, Lynch CF, Allmer C, Slager SL, Lossos IS, Chanock SJ, Rothman N, Hartge P, Dogan A, Wang SS. Leuk Lymphoma. 2012
• The spectrum of B-cell lymphoma, unclassifiable, with features intermediate between diffuse large B-cell lymphoma and classical Hodgkin lymphoma: a description of 10 cases. Gualco G, Natkunam Y, Bacchi CE. Mod Pathol. 2012