Clinical Focus

• General Surgery
• Kidney and Pancreas Transplantation
• Liver Transplantation

Administrative Appointments

• Director Adult Kidney and Pancreas Transplant Program, Stanford University School of Medicine (2001 - present)

Professional Education

Current Research Interests

My research interest is centered on the improvement of clinical immunosuppression. This involves the evaluation of new immunosuppressive drugs that are potentially more efficacious and/or less toxic or better monitoring of the effect of these drugs. We are participating in the drug development process from phase1 to phase 3 studies. I participate to trial design and data analysis of some of these trials. The ultimate goal is to achieve tolerance, a state that would obviate the need for any drugs. I am a clinical investigator in a multidisciplinary trial aimed at inducing tolerance after kidney transplantation. My other interests include the development and study of efficacy of strategies to desensitized organ transplant recipients and expending our capabilities to tailor the immunosuppression needs of specific patients through new immune-monitoring tests. Ultimately these research projects are aimed at improving the outcomes of organ transplant recipients.

Clinical Trials

• Combined Blood Stem Cell and HLA Haplotype Match Living Donor Kidney Transplantation Recruiting

Publications

• Tolerance and Withdrawal of Immunosuppressive Drugs in Patients Given Kidney and Hematopoietic Cell Transplants. Scandling JD, Busque S, Dejbakhsh-Jones S, Benike C, Sarwal M, Millan MT, Shizuru JA, Lowsky R, Engleman EG, Strober S. Am J Transplant. 2012
• Living donor evaluation and exclusion: the Stanford experience. Lapasia JB, Kong SY, Busque S, Scandling JD, Chertow GM, Tan JC. Clin Transplant. 2011 Sep-Oct; 25 (5): 697-704
• C1q-fixing human leukocyte antigen antibodies are specific for predicting transplant glomerulopathy and late graft failure after kidney transplantation. Yabu JM, Higgins JP, Chen G, Sequeira F, Busque S, Tyan DB. Transplantation. 2011; 91 (3): 342-7
• Debate: PRO Position. Formal assessment of donor kidney function should be mandatory. Tan JC, Busque S, Ho B, Myers BD. Am J Nephrol. 2011; 33 (3): 198-200; discussion 205
• Incidental kidney stones: a single center experience with kidney donor selection. Kim IK, Tan JC, Lapasia J, Elihu A, Busque S, Melcher ML. Clin Transplant. 2011