Clinical Focus

• Neurology

Professional Education

Postdoctoral Advisees

Julie Nantel

Graduate & Fellowship Program Affiliations

• Neurosciences
• Neurosurgery
• Bioengineering

Current Research Interests

My research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.

Clinical Trials

• Safety and Efficacy Study of GAD Gene Transfer Therapy in Parkinson's disease No longer recruiting

Publications

• Deep brain stimulation in "on"-state Parkinson hyperpyrexia. Klepitskaya O, Cole W, Henderson J, Bronte-Stewart H. Neurology. 2011; 76 (7 Suppl 2): S69-71
• Effect of medication and STN-DBS on postural control in subjects with Parkinson's disease. Nantel J, McDonald JC, Bronte-Stewart H. Parkinsonism Relat Disord. 2011
• Human subthalamic neuron spiking exhibits subtle responses to sedatives. Maciver MB, Bronte-Stewart HM, Henderson JM, Jaffe RA, Brock-Utne JG. Anesthesiology. 2011; 115 (2): 254-64
• Inclusion and exclusion criteria for DBS in dystonia. Bronte-Stewart H, Taira T, Valldeoriola F, Merello M, Marks WJ, Albanese A, Bressman S, Moro E. Mov Disord. 2011: 26 Suppl 1 S5-16
• Maximal subthalamic beta hypersynchrony of the local field potential in Parkinson's disease is located in the central region of the nucleus. de Solages C, Hill BC, Yu H, Henderson JM, Bronte-Stewart H. J Neurol Neurosurg Psychiatry. 2011; 82 (12): 1387-9